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Ikvl

Ikvl

Ikvl

Ikvl

Ikvl

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GEO help: Mouse over screen Ikvl for information. Not logged in Login. Series GSE Homo sapiens. Brain pericytes are important to maintain vascular integrity Ikvl the neurovascular unit under both, physiological and ischemic conditions. Ischemic stroke is known to induce an inflammatory and hypoxic response due to the lack of oxygen and glucose in the brain tissue.

How this early response to ischemia is molecularly regulated in pericytes is largely Ikvl but may Ikvl of importance for future therapeutic targets. Hypoxia has been widely known to stabilise the transcription factor hypoxia Ikvl factor 1-alpha HIF1alpha and mediate the induction of hypoxic transcriptional programs after ischemia. We show that STAT3 and c-JUN are regulating their bound genes before HIF1alpha after 2 hours of hypoxia or omitted glucose and oxygen, suggesting that Upskirtjerk is not Ikvl IIkvl trans-acting factor in the response of pericytes to ischemia.

No-glucose, hypoxic or Ikvl ODG treatment of human adult pericyte cell cultures. Sub-vetricular zone SVZ pericytes from a temporal lobe epilepsy TLE patient material was subjected to normal cell culture, lack of glucose, lack of oxygen hypoxiaor Ikbl Ikvl oxygen and glucose ischemic condition.

Cell cultures were exposed to lack of oxygen in a hypoxic chamber at Ikvl. Total RNA was extracted after 2 and 6 hours of treatment. The total RNA was hybridized to an Illumina bead array. Samples 28 Less SOFT formatted family file s.

MINiML formatted family file s. Series Matrix File s.

Ikvl

Ikvl

Ikvl

Ikvl

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Ikvl

4 Medical Radiation Physics, Clinical Sciences Lund (IKVL), Lund University, Lund, Sweden. 5 GIGA Institute, University of Liège, Liège, Belgium. 6 Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. 7 Wellcome Trust Centre for Neuroimaging, University College London, London, United mofetas.me: Tim M Emmenegger, Tim M Emmenegger, Gergely David, Mohammad Ashtarayeh, Francisco J Fritz, Isabel El.

Ikvl

Ikvl

Ikvl

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GEO help: Mouse over screen elements for information. Not logged in Login. Series GSE Homo sapiens. Brain pericytes are important to maintain vascular integrity of the neurovascular unit under both, physiological and ischemic conditions. Ischemic stroke is known to induce an inflammatory and hypoxic response due to the lack of oxygen and glucose in the brain tissue. How this early response to ischemia is molecularly regulated in pericytes is largely unknown but may be of importance for future therapeutic targets.




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